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Effective Dose – amount of substance required to produce
a response on a given percentage of test subjects
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ED50 or effective dose-50% – the amount of substance
that is required in order to cause the effect in 50% of the population of test subjects.
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LD50 or lethal dose-50% – the amount of substance
needed in order to kill 50% of the test population.
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Threshold Level – the dose that has no measurable response
(1). The threshold level also determines the safe dose that can be absorbed without negative effects.